{"id":8190,"date":"2020-04-21T16:32:54","date_gmt":"2020-04-21T16:32:54","guid":{"rendered":"https:\/\/nanovea.com\/?p=8190"},"modified":"2023-11-13T23:24:07","modified_gmt":"2023-11-13T23:24:07","slug":"biyolojik-doku-sertlik-degerlendirme-kullanarak-nanoindentasyon","status":"publish","type":"post","link":"https:\/\/nanovea.com\/tr\/biological-tissue-hardness-evaluation-using-nanoindentation\/","title":{"rendered":"Nanoindentasyon ile Biyolojik Doku Sertlik De\u011ferlendirmesi"},"content":{"rendered":"
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Biyolojik Doku Nanoindentasyonunun \u00d6nemi <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Geleneksel mekanik testler (sertlik, yap\u0131\u015fma, s\u0131k\u0131\u015ft\u0131rma, delinme, akma dayan\u0131m\u0131 vb.), dokulardan k\u0131r\u0131lgan malzemelere kadar \u00e7ok \u00e7e\u015fitli geli\u015fmi\u015f malzemelerin bulundu\u011fu g\u00fcn\u00fcm\u00fcz\u00fcn kalite kontrol ortamlar\u0131nda daha fazla hassasiyet ve g\u00fcvenilirlik gerektirir. Geleneksel mekanik enstr\u00fcmantasyon, geli\u015fmi\u015f malzemeler i\u00e7in gereken hassas y\u00fck kontrol\u00fcn\u00fc ve \u00e7\u00f6z\u00fcn\u00fcrl\u00fc\u011f\u00fc sa\u011flayamamaktad\u0131r. Biyomalzemelerle ilgili zorluklar, son derece yumu\u015fak malzemeler \u00fczerinde do\u011fru y\u00fck kontrol\u00fc yapabilen mekanik testlerin geli\u015ftirilmesini gerektirmektedir. Bu malzemeler, uygun \u00f6zellik \u00f6l\u00e7\u00fcm\u00fcn\u00fc sa\u011flamak i\u00e7in geni\u015f derinlik aral\u0131\u011f\u0131na sahip \u00e7ok d\u00fc\u015f\u00fck mN alt\u0131 test y\u00fckleri gerektirir. Buna ek olarak, bir\u00e7ok farkl\u0131 mekanik test t\u00fcr\u00fc tek bir sistem \u00fczerinde ger\u00e7ekle\u015ftirilebilir ve bu da daha fazla i\u015flevsellik sa\u011flar. Bu, biyomalzemeler \u00fczerinde \u00e7izilme direnci ve akma dayan\u0131m\u0131 hata noktalar\u0131na ek olarak sertlik, elastik mod\u00fcl, kay\u0131p ve depolama mod\u00fcl\u00fc ve s\u00fcr\u00fcnme dahil olmak \u00fczere bir dizi \u00f6nemli \u00f6l\u00e7\u00fcm sa\u011flar.<\/p>\n

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\u00d6l\u00e7\u00fcm Hedefi<\/p>\n

Bu uygulamada Nanovea'n\u0131n nanoindentasyon modundaki mekanik test cihaz\u0131, prosciutto'nun ya\u011f, a\u00e7\u0131k et ve koyu et b\u00f6lgelerinde bir biyomalzeme ikamesinin 3 ayr\u0131 alan\u0131n\u0131n sertli\u011fini ve elastik mod\u00fcl\u00fcn\u00fc incelemek i\u00e7in kullan\u0131lm\u0131\u015ft\u0131r.<\/p>\n

Nano indentasyon, ASTM E2546 ve ISO 14577 enstr\u00fcmanl\u0131 indentasyon standartlar\u0131na dayanmaktad\u0131r. Bilinen geometriye sahip bir girinti ucunun, kontroll\u00fc artan normal y\u00fck ile test malzemesinin belirli bir b\u00f6lgesine s\u00fcr\u00fcld\u00fc\u011f\u00fc yerle\u015fik y\u00f6ntemleri kullan\u0131r. \u00d6nceden ayarlanm\u0131\u015f bir maksimum derinli\u011fe ula\u015f\u0131ld\u0131\u011f\u0131nda, tamamen gev\u015feme ger\u00e7ekle\u015fene kadar normal y\u00fck azalt\u0131l\u0131r. Y\u00fck, bir piezo akt\u00fcat\u00f6r taraf\u0131ndan uygulan\u0131r ve y\u00fcksek hassasiyetli bir y\u00fck h\u00fccresi ile kontroll\u00fc bir d\u00f6ng\u00fcde \u00f6l\u00e7\u00fcl\u00fcr. Deneyler s\u0131ras\u0131nda numune y\u00fczeyine g\u00f6re indenter pozisyonu y\u00fcksek hassasiyetli kapasitif sens\u00f6r ile izlenir. Elde edilen y\u00fck ve yer de\u011fi\u015ftirme e\u011frileri, test edilen malzemenin mekanik yap\u0131s\u0131na \u00f6zg\u00fc veriler sa\u011flar. Olu\u015fturulan modeller, \u00f6l\u00e7\u00fclen verilerle kantitatif sertlik ve mod\u00fcl de\u011ferlerini hesaplar. Nanoindentasyon, nanometre \u00f6l\u00e7eklerinde d\u00fc\u015f\u00fck y\u00fck ve penetrasyon derinli\u011fi \u00f6l\u00e7\u00fcmleri i\u00e7in uygundur.<\/p>\n

Sonu\u00e7lar ve Tart\u0131\u015fma<\/i><\/u><\/p>\n

A\u015fa\u011f\u0131daki tablolar sertlik ve Young mod\u00fcl\u00fcn\u00fcn \u00f6l\u00e7\u00fclen de\u011ferlerini ortalamalar ve standart sapmalarla birlikte sunmaktad\u0131r. Y\u00fcksek y\u00fczey p\u00fcr\u00fczl\u00fcl\u00fc\u011f\u00fc, k\u00fc\u00e7\u00fck girinti boyutu nedeniyle sonu\u00e7larda b\u00fcy\u00fck de\u011fi\u015fikliklere neden olabilir.
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Ya\u011f b\u00f6lgesi et b\u00f6lgelerinin yakla\u015f\u0131k yar\u0131s\u0131 kadar sertli\u011fe sahipti. Et muamelesi koyu renkli et alan\u0131n\u0131n a\u00e7\u0131k renkli et alan\u0131ndan daha sert olmas\u0131na neden olmu\u015ftur. Elastik mod\u00fcl ve sertlik, ya\u011f ve et b\u00f6lgelerinin a\u011f\u0131zda hissedilen \u00e7i\u011fnenebilirli\u011fi ile do\u011frudan ili\u015fkilidir. Ya\u011fl\u0131 ve a\u00e7\u0131k renkli et b\u00f6lgeleri 60 saniye sonra koyu renkli ete g\u00f6re daha y\u00fcksek oranda s\u00fcnmeye devam etmi\u015ftir.
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Detayl\u0131 Sonu\u00e7lar - Ya\u011f<\/strong><\/em><\/p>\n\n

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Detayl\u0131 Sonu\u00e7lar - Hafif Et
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Detayl\u0131 Sonu\u00e7lar - Koyu Et<\/strong><\/em><\/p>\n\n

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Sonu\u00e7<\/p>\n

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Bu uygulamada Nanovea'n\u0131n mekanik test cihaz\u0131<\/a> nanoindentasyon modunda, y\u00fcksek numune y\u00fczey p\u00fcr\u00fczl\u00fcl\u00fc\u011f\u00fcn\u00fcn \u00fcstesinden gelirken ya\u011f ve et alanlar\u0131n\u0131n mekanik \u00f6zelliklerini g\u00fcvenilir bir \u015fekilde belirledi. Bu, Nanovea'n\u0131n mekanik test cihaz\u0131n\u0131n geni\u015f ve e\u015fsiz kapasitesini ortaya koydu. Sistem ayn\u0131 anda son derece sert malzemeler ve yumu\u015fak biyolojik dokular \u00fczerinde hassas mekanik \u00f6zellik \u00f6l\u00e7\u00fcmleri sa\u011flar.<\/p>\n

Piezo tabla ile kapal\u0131 d\u00f6ng\u00fc kontrol\u00fcndeki y\u00fck h\u00fccresi, sert veya yumu\u015fak jel malzemelerin 1 ila 5kPa aras\u0131nda hassas \u00f6l\u00e7\u00fcm\u00fcn\u00fc sa\u011flar. Ayn\u0131 sistemi kullanarak, biyomalzemeleri 400N'ye kadar daha y\u00fcksek y\u00fcklerde test etmek m\u00fcmk\u00fcnd\u00fcr. Yorulma testi i\u00e7in \u00e7ok d\u00f6ng\u00fcl\u00fc y\u00fckleme kullan\u0131labilir ve d\u00fcz silindirik bir elmas u\u00e7 kullan\u0131larak her b\u00f6lgedeki akma dayan\u0131m\u0131 bilgileri elde edilebilir. Ayr\u0131ca, Dinamik Mekanik Analiz (DMA) ile viskoelastik \u00f6zellikler kay\u0131p ve depolama mod\u00fclleri, kapal\u0131 d\u00f6ng\u00fc y\u00fck kontrol\u00fc kullan\u0131larak y\u00fcksek do\u011frulukla de\u011ferlendirilebilir. Ayn\u0131 sistem \u00fczerinde \u00e7e\u015fitli s\u0131cakl\u0131klarda ve s\u0131v\u0131lar alt\u0131nda testler de yap\u0131labilmektedir.<\/p>\n

Nanovea'n\u0131n mekanik test cihaz\u0131 biyolojik ve yumu\u015fak polimer\/jel uygulamalar\u0131 i\u00e7in \u00fcst\u00fcn bir ara\u00e7 olmaya devam ediyor.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\u015eIMDI, BA\u015eVURUNUZ HAKKINDA KONU\u015eALIM<\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tCANLI SOHBET<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Importance of Biological Tissue Nanoindentation Traditional mechanical tests (hardness, adhesion, compression, puncture, yield strength, etc.) require greater precision and reliability in today\u2019s quality control environments with a wide range of advanced materials from tissues to brittle materials. Traditional mechanical instrumentation fails to provide the sensitive load control and resolution required for advanced materials. The challenges […]<\/p>\n","protected":false},"author":1,"featured_media":11687,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[7,338,349,337],"tags":[],"class_list":["post-8190","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-application-notes","category-indentation-hardness-elastic","category-laboratory-testing","category-mechanical-testing"],"_links":{"self":[{"href":"https:\/\/nanovea.com\/tr\/wp-json\/wp\/v2\/posts\/8190","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nanovea.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nanovea.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nanovea.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nanovea.com\/tr\/wp-json\/wp\/v2\/comments?post=8190"}],"version-history":[{"count":20,"href":"https:\/\/nanovea.com\/tr\/wp-json\/wp\/v2\/posts\/8190\/revisions"}],"predecessor-version":[{"id":23480,"href":"https:\/\/nanovea.com\/tr\/wp-json\/wp\/v2\/posts\/8190\/revisions\/23480"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nanovea.com\/tr\/wp-json\/wp\/v2\/media\/11687"}],"wp:attachment":[{"href":"https:\/\/nanovea.com\/tr\/wp-json\/wp\/v2\/media?parent=8190"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nanovea.com\/tr\/wp-json\/wp\/v2\/categories?post=8190"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nanovea.com\/tr\/wp-json\/wp\/v2\/tags?post=8190"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}